Is It Safe To Smoke Weed While On Antibiotics?

You don’t want the antibiotics you’ve been given to be neutralized, nor do you want to have larger or lower amounts of prescription or cannabis than is recommended. If your doctor recommends an antibiotic, you must finish the entire course of treatment to ensure that your infection is entirely eradicated and to avoid the chance of developing resistance to antibiotics in your body.

But can you smoke weed on antibiotics? Thankfully, the research so far suggests that cannabis does not appear to interfere significantly with antibiotics. When taken concurrently, the antibiotic Rifampin can lower CBD levels.

What are the Consequences of Smoking Weed While on Antibiotics?

Based on current research, antibiotics are likely to remain effective, but that doesn’t mean they’re without risk. It’s critical to realize that different medications utilize different liver metabolic pathways. Many prescription medications, including certain antibiotics, employ the same metabolic pathway to metabolize cannabis.

Can you smoke weed on antibiotics? The quick answer is yes. Although they share several metabolic pathways, most medicines have no harmful interactions with cannabis. If they occur, the interactions have been described as non-life-threatening so far.

The lengthier answer is that no one knows for sure because adequate testing and study on cannabis and its complete effects on the body, including interactions with other pharmaceutical treatments, has yet to be undertaken. It’s also crucial to keep in mind that everyone is unique. However, this is not to argue that cannabis use is without risk.

Short-term side effects include dizziness, weariness, dry mouth, and cognitive impairment, whereas long-term consequences of cannabis remain unknown.

Marijuana Substitutes While on Antibiotics

While cannabis is unlikely to interact poorly with antibiotics, some people who are taking antibiotics may want to investigate alternatives to marijuana. Consuming cannabidiol (CBD) isolate products instead of full- and broad-spectrum CBD products could be a potential approach. As a result, the hazards are minimized because there are fewer psychotropic and intoxicating cannabinoids. Furthermore, scientists have discovered that it has the potential to become its own antibiotic in the future.

CBD “killed all the kinds of bacteria they examined in a lab, including several that were highly resistant to known antibiotics,” according to a study led by Mark Blaskovich. Even after 20 days of CBD consumption, the study observed no build-up of resistance, which is even more impressive when considering CBD as an antibiotic option.

The researchers also discovered that CBD is effective against biofilms (which could include dental plaque), four Gram-negative bacteria (including those that cause gonorrhea, meningitis, and respiratory infections including bronchitis and pneumonia), and MRSA.


If you’re on antibiotics and don’t want to use cannabis, other botanicals that contain helpful cannabinoids can be used instead. Always notify your doctor if you’re taking any supplements, and remember that neither these nor cannabis can substitute antibiotics.

Before doing so, you should contact your doctor, although taking antibiotics while also consuming cannabis is likely to be fine with them. It also assumes you’re not exacerbating a lung infection using inhalational methods and that you’re aware of antibiotic side effects and the potential for cannabis-related side effects. Physicians are specialists on the antibiotics being prescribed, so they’ll be able to tell you whether or not they’re right for you.

Regardless of where cannabis is legal, you may always ask your doctor questions, and your talks will be kept private. Your doctor will give you medical advice without making any legal conclusions. Also, keep in mind that if you’re still unsure after speaking with your primary care physician, you can seek a second opinion.

Finally, to reduce the negative effects of high-THC cannabis, it is preferable to consume it with caution and moderation at first, avoiding combustion-based methods of consumption and switching to CBD-only products for the duration of the antibiotic course.

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